Hybrid dogs ,also referred to as mixed dog breeds or designer dogs, are growing in popularity. In short, a designer dog is a purposeful mix of two purebreds. Many are bred to get a particular trait, such as less shedding or hypoallergenic.
A designer dog offers pet owners a rare and unique breed. However, proceed with caution when choosing a hybrid, as you never know which undesirable breed behaviors will be dominant. It's important to be sure to do your research on breeders, as well as make sure both breed types fit your lifestyle and family.
The Pros
One of the advantages of designer dogs is the sheer number of varieties available. More than 200 different hybrid combinations exist, which means there is a designer dog for every taste. Most of these hybrids are small and designed to have good personality combined with adorability.
Designer dogs are created to fit every need — from pocket-size dogs for easy travel to low-shed dogs for those with allergies. Many of these designer-dog creations are free of some of the traits that can make life difficult for the purebred dog. For example, some purebreds, like the Pug, have a very short snout, making breathing difficult. But the popular Puggle — the hybrid of a Pug and a Beagle — has a longer nose while still maintaining the Pug’s wrinkled forehead and loopy gait.
Many hybrid breeders claim their dogs have hybrid vigor, a strength that comes from having parents of two different breeds. The offspring of two different breeds rarely inherit genetic defects, because the bloodlines aren’t as close as those of purebreds.
For example, many retriever breeds tend to have cataracts or epilepsy, many large-breed dogs have hip dysplasia, and many small-breed dogs are prone to dental problems. Mixed-breed dogs rarely inherit these genetic defects, because their genetics are more varied. (Incidentally, this is true of all mixed-breed dogs, not just designer dogs or hybrids.)
The cons

The major con of designer dogs is the price. Most designer dogs cost upwards of $700, whereas many purebred dogs begin at $250. (Of course, mixed breed dogs are widely available for adoption, typically at prices set by rescue groups or animal shelters.)
Although each designer dog was bred for specific appearance and traits, there’s a good chance that some or all of them will not develop in the offspring. Mixing breeds is chancy, because the outcome is not absolute. Although purebred dog offspring will always mature to appear like the parent dogs, the hybrid offspring may appear more like one parent than the other, or have a personality more like one parent than the other.
So, although you might be searching for a small Yorkipoo, the pup might grow up to be the size of a large Yorkshire Terrier instead of a Teacup Poodle.